Peer-Reviewed Publications

Noninvasive mathematical analysis of spectral electrocardiographic components for coronary lesions of intermediate to obstructive stenosis severity–relationship with classic and functional SYNTAX score

Catheterization Cardiovascular Interventions, Volume 86, Issue 1, July 2015, Pages 21–29

The Diagnostic Performance of Multifunction Cardiogram (MCG) in Functional Myocardial Ischemia

Annals of Noninvasive Electrocardiology / Volume 20, Issue 5, pages 508–510, September 2015

TCTAP A-086 Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the Multifunction-CardioGram (MCG), to Coronary Angiography or MDCT, SPECT for the Detection of Revalent Coronary Artery Stenosis

J Am Coll Cardiol. 2015;65(17_S):S45-S45. doi:10.1016/j.jacc.2015.03.148

Non-invasive assessment of functionally significant coronary stenoses through mathematical analysis of spectral ECG components

Open Heart 2014;1: doi:10.1136/openhrt-2014-000144

A Paired-Comparision of the MultiFunction CardioGrams (MCG) and SPECT Myocardial Perfusion Imaging (MPI)

International Journal of Medical Sciences 2011;8(8):717-72

Comparing MCG and Coronary Angiography for detection of Coronary Artery Stenosis in Women

Treatment Strategies – Cardiology Volume 3, Issue 1 pp.82-91

Appropriateness Guidelines for the use of MCG in clinical settings are currently being revised in conjunction with the American College of Computational Electrophysiology. New guidelines will be posted shortly.

An analysis of the Asian Multi-Center Trial

Congestive Heart Failure 2008 14: 251-260

A Meta-Analysis of the MCG clinical trials

International Journal of Medical Sciences April 2009 6(4):143-155

An analysis of the Siegburg clinical trial (post-revascularization)

International Journal of Medical Sciences 2008 5(2): 50-61

An analysis of the Siegburg clinical trial (no revascularization)

International Journal of Medical Sciences 2007 4(5): 249-263

An analysis of the Westchester clinical trial

Heart Disease 2002 4: 2-12

Peer-Reviewed Abstracts and Presentations

An analysis of the effect of age, gender and revascularization on MCG results
(Based upon the Siegburg studies) Circulation 2007 116: II_367

A comparison of the MCG system to coronary angiography

American College of Chest Physicians October 2007 132(4): 466S
(Based upon the Post-Revascularization Siegburg study)

Invited Talks

American College of Cardiology 2011
Dr. John Strobeck presented a poster session comparing the accuracy of MCG to Myocardial Perfusion Imaging (MPI / Nuclear Stress Imaging).

The following peer-reviewed studies do not include a focus on the MCG, but provide large-scale clinical evidence for the need of appropriate, accurate technology for risk-stratifying patients who present with chest pain and heart disease symptoms to the hospital ER.

Cardiac Imaging Tests Beget More Tests, but No Benefit.

Michael O’Riordan, Medscape, February 10, 2014.

Low Diagnostic Yield of Elective Coronary Angiography.

Manesh R. Patel, M.D., Eric D. Peterson et al. N Engl J Med 2010; 362:886-895 DOI: 10.1056/NEJMoa0907272